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Dr. Robert Jaffe Represents The Endocrine Society and The Hormone Foundation During Public Comment Section
October 24, 2002 — Robert B. Jaffe, M.D., President of The Hormone Foundation and a member of The Endocrine Society's Council, today spoke about hormone replacement therapy at the National Institutes of Health Scientific Workshop on Menopausal Hormone Therapy. The workshop was held to review the recent results from a portion of the Women's Health Initiative (WHI) clinical trial that studied combination estrogen and progestin therapy and was recently halted. In addition, the conference compared the results of other federally funded research on menopausal combination hormonal treatment and sought to help clinicians and patients understand the implications of current knowledge on decisions regarding short- and long-term use of hormonal treatment. In his presentation on behalf of The Endocrine Society and The Hormone Foundation, Dr. Jaffe, who is the Fred Gellert Professor of Reproductive Medicine and Biology at the University of California in San Francisco, discussed the impact that recently released hormonal treatment studies, such as the WHI, have had on patients who take or are considering taking combined estrogen and progestin treatment. "The new research that has come out over the past few months has caused distress and confusion for millions of women, and it has changed the way that doctors practice medicine when it comes to menopause," said Dr. Jaffe. "I believe that it is essential for the medical community to translate these new data so that patients can understand how this information will impact their health care and doctors will understand the best ways to treat postmenopausal patients in the future." Additionally, Dr. Jaffe discussed the need to examine lifestyle issues, such as good nutrition, weight loss when appropriate, adequate exercise, no smoking and drinking in moderation as important for optimizing postmenopausal health.
"As we further examine lifestyle and postmenopausal health, I think that we will find that a healthy lifestyle may be as important as pharmaceuticals," said Dr. Jaffe.
Following the results of the WHI and Heart and Estrogen/Progestin Replacement (HERS) Studies, which were both announced in July, both The Endocrine Society and The Hormone Foundation worked to communicate the findings to doctors and patients. Dr. Jaffe drafted a patient question and answer document for The Hormone Foundation's Web site. The document translates the key findings of the WHI and HERS studies for patients, including the reasons why the estrogen and progestin portion of the WHI study was stopped early and the risks that both HERS and WHI discovered for women taking estrogen and progestin. The document is also available for physicians to download and share with their patients who may be confused and frightened by the new hormonal treatment findings.
Dr. Jaffe also emphasized the need for additional research into hormonal treatment, specifically mentioning the need for future research that addresses the complex biochemical mechanisms of estrogen and progesterone action, whether the results were specific to the estrogen and progestin studied, and the effects of hormone treatment on menopausal symptoms such as hot flashes and vaginal dryness. "In the future, new studies are also needed to define the benefits of hormonal treatment in perimenopausal and early menopausal women," Dr. Jaffe noted. "These types of studies will help the medical community understand which women will benefit from hormonal treatment and which ones are at risk in specific populations." Dr. Jaffe's presentation was part of a public comment and discussion section on the second day of the workshop. Other organizations that were invited to present during this section included the American College of Obstetricians and Gynecologists, the North American Menopause Society, the National Medical Association, the American Academy of Family Physicians and the American Society for Bone and Mineral Research.
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