RELATION OF ANEMIA AT DISCHARGE TO SURVIVAL AFTER ACUTE CORONARY SYNDROMES

J Vaglio, DM Safley, M Rahman, M Kosiborod, P Jones, R Thompson, HM Krumholz, and JA Spertus

Am J Cardiol,August 15, 2005; 96(4): 496-9.

Two-year survival rate was assessed among 1,038 patients who had acute coronary syndromes that were classified by discharge hematocrit values as normal (>39%, n = 360, 34.7%), mildly anemic (33.1% to 39%, n = 430, 41.4%), or moderately/severely anemic (< or = 33%, n = 248, 23.9%). Worsening anemia was associated with a decreased 2-year survival rate (normal 95.8%, mild anemia 91.2%, moderate/severe anemia 81.5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia.

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